EBOO therapy is rare. EBOO therapy in a licensed, oceanfront, luxury healing sanctuary — surrounded by jungle, ocean, and a fully integrated holistic team — is found nowhere else in the world. This is what Sanctuary Tulum was built to deliver.

EBOO therapy benefits — extracorporeal blood oxygenation and ozonation at Sanctuary Tulum
Medically supervised EBOO therapy at Sanctuary Tulum

A Setting That Heals

Detoxification is as much nervous-system work as it is biochemical. The body cannot release deeply held toxins while it is in fight-or-flight. At Sanctuary Tulum, every EBOO session is performed in a private oceanfront medical suite, with sound therapy, breathwork, and an attending physician. Outside the door is a cenote, the Caribbean, and the slowest pace of life you've ever experienced.

eboo therapy white marble medical blood filtration — EBOO extracorporeal blood oxygenation and ozonation therapy at Sanctuary Tulum

A Fully Integrated Stack

EBOO therapy is one component of a much larger system that includes Brain Repair IV, NAD+, stem cell therapy, HBOT, sacred plant medicine, and the proprietary Pouyan Method™.

For the Few Who Want the Best

EBOO is included in our Gold and Platinum healing packages. To explore a fully personalized stay, view our private packages or apply directly.

Clinical Screening Before Any Protocol

Every prospective guest completes a confidential clinical intake and full medical screening before any ceremony, high-dose IV, or regenerative protocol is scheduled. The intake reviews current medications, medical history, cardiovascular status, and mental health history. Where a client is currently prescribed SSRIs, SNRIs, MAO inhibitors, benzodiazepines, opioids, or lithium, the medical team plans a documented taper or pause window with the treating physician before EBOO therapy in a luxury Tulum setting work begins. Sanctuary Tulum never advises guests to discontinue prescribed medication on their own.

On-Site Medical Oversight

A physician is on site, supported by registered nurses, IV therapy specialists, and integrative practitioners. Vitals are monitored across every physician-supervised session — blood pressure, oxygen saturation, and cardiac rhythm where clinically indicated — with emergency medications and airway equipment on hand. Credentialing detail lives on the Medical Review Board page, and a broader description of the safety approach is on the safest psychedelic facility page. Guests are welcome to review both before deciding whether the program fits them.

How EBOO therapy in a luxury Tulum setting Fits the Full Program

The EBOO therapy program integrates biological, neurological, and psychological work rather than isolating one modality. That means medical stabilization first, followed by a physician-scheduled combination of IV therapy, HBOT, nutrition, and — where clinically appropriate — medically supervised ibogaine therapy program, medically supervised ayahuasca ceremonies, 5-MeO-DMT, or psilocybin therapy. The exact sequence is set individually — one guest's program rarely looks identical to another's.

Integration and Aftercare

A stay is only useful if it holds. Every program ends with a written integration and aftercare plan — continued one-on-one check-ins with the integration team, referral to trauma-informed practitioners at home when appropriate, and lifestyle protocols covering nutrition, sleep, movement, and nervous-system regulation. Guests are encouraged to keep their existing relationships with a treating physician and to return for booster stays when a specific life transition benefits from it. For a full overview of the sanctuary philosophy, read about the proprietary Pouyan Method™.

What a Typical Day Looks Like

Days at Sanctuary Tulum are structured but not rushed. Guests wake in an oceanfront suite, take a slow start with breath practice and light movement on the beach, then move into the first clinical block of the day. That block is set by the medical team the night before based on the guest's current labs, sleep quality, and how the previous day landed. It might be an amino-acid or NAD+ IV, an HBOT session, a red-light exposure, a physician review, or a preparation session for an upcoming ceremony. Meals are organic, plant-forward, and served privately rather than in a group dining hall. Afternoons often include one-on-one integration time, targeted Pouyan Method™ protocols, and time in the ocean. Evenings are quiet — nervous-system regulation matters as much as any active intervention. This whole-day rhythm is the reason the program is described as residential rather than outpatient, and it is central to how EBOO ozone therapy actually holds.

Who Benefits Most

The EBOO therapy program is a strong fit for adults who have already tried the conventional route — repeated outpatient care, several rounds of medication, one or more short-stay rehab or hospital admissions — and are looking for a fundamentally different model. It is also a fit for people arriving without any prior treatment who prefer to start with an integrative, physician-supervised program rather than default to pharmaceutical management. It is not a fit for active psychosis, unstable cardiac disease, or acute suicidal crisis — those cases require conventional hospital care first, and the admissions team will say so honestly during the confidential intake. For a wider view of how the sanctuary works with different clinical pictures, see the What Makes Us Different and All Treatments pages, along with our Medical Review Board.

Honest Limits and Expectations

No ethical program guarantees outcomes, and Sanctuary Tulum does not. What the program does guarantee is a fully staffed, licensed medical environment, protocols that are individualized rather than templated, and continued relationship with the integration team after the guest goes home. Guests are asked to keep their existing relationships with their treating clinicians throughout the process, to be honest at intake about current medications and prior treatment history, and to give the program the length of stay the medical team recommends. Shortening a stay to fit a work calendar is the most common reason a guest walks away with a partial result. If cost, logistics, or timing are constraints, the admissions team will say so during the confidential call — the honest conversation is more useful than a brochure.

Questions Guests Often Ask Before Booking

Prospective guests frequently ask how EBOO compares to a standard IV ozone protocol, and the answer is scale: EBOO filters and treats the entire circulating blood volume across a session, rather than the smaller volume typical of a direct IV ozone infusion. They also ask about discomfort — most guests describe the sensation as similar to a standard blood draw at each access point, with no discomfort during the filtration itself. And they ask what a realistic course looks like: most guests receive between two and six sessions during a stay, spaced according to how their bloodwork and symptoms respond, never on a fixed schedule set in advance of that data.

We are also asked whether EBOO is appropriate as a stand-alone visit rather than part of a residential stay. It can be, for guests who are otherwise healthy and simply want a periodic detox protocol, but the deeper value comes from combining it with the broader luxury detox structure — labs, nutrition, and follow-up — rather than a single isolated session.

EBOO in Tulum is delivered inside our comprehensive luxury wellness center program, where blood purification is layered with plant medicine preparation, IV therapy, and clinical detox.